Cytochalasin D
Supplier:
Catalogue number:
10-2071-02
Size:
5 mg
Product is available in:
Disrupts actin filaments / Potent inhibitor of actin polymerization which also causes the disruption of actin filaments. More potent that cytochalasin B (10-fold) and does not inhibit monosaccharide transport across cell membranes. Disruption of actin microfilaments leads to activation of p53. Cell permeable
Product Type:
Biochemicals & reagents
CAS Number:
22144-77-0
Reference:
1) Goddetteand et al. (1986), Actin polymerization. The mechanism of action of cytochalasin D ; J. Biol. Chem., 261 15974 / 2) Rubtsova et al. (1998), Disruption of actin microfilaments by cytochalasin D leads to activation of p53 ; FEBS Lett., 430 353
Storage Temperature:
-20°C
Additional Information:
TARGET: Cytoskeleton; Antibiotic -- PATHWAY: Cell cycle; p53; Apoptosis inducer -- RESEARCH AREA: Cell death