www.mayflowerbio.com
Sales & Support: 314-485-5210

*

Cytochalasin D

Supplier:
Catalogue number:
10-2071-01
Size:
1 mg
Product is available in:
  • USA
  • Canada
$68.00 Shipping is calculated in checkout

Disrupts actin filaments / Potent inhibitor of actin polymerization which also causes the disruption of actin filaments. More potent that cytochalasin B (10-fold) and does not inhibit monosaccharide transport across cell membranes. Disruption of actin microfilaments leads to activation of p53. Cell permeable

Product Type:

Biochemicals & reagents

CAS Number:

22144-77-0

Reference:

1) Goddetteand et al. (1986), Actin polymerization. The mechanism of action of cytochalasin D ; J. Biol. Chem., 261 15974 / 2) Rubtsova et al. (1998), Disruption of actin microfilaments by cytochalasin D leads to activation of p53 ; FEBS Lett., 430 353

Storage Temperature:

-20°C

Additional Information:

TARGET: Cytoskeleton; Antibiotic -- PATHWAY: Cell cycle; p53; Apoptosis inducer -- RESEARCH AREA: Cell death