Stauprimide
Supplier:
Catalogue number:
10-1189-01
Size:
1 mg
Product is available in:
Primes stem cells for differentiation / Stauprimide dramatically primes embryonic stem cells for differentiation. Its molecular target is NME2, a c-Myc-activating transcription factor. Stauprimide inhibits nuclear localization of NME2 thereby downregulating c-Myc.
Product Type:
Biochemicals & reagents
CAS Number:
154589-96-5
Reference:
1) Zhu et al. (2009), A small molecule primes embryonic stem cells for differentiation; Cell Stem Cell, 4 416 2) Zaret et al. (2009), Using small molecules to great effect in stem cell differentiation; Cell Stem Cell, 4 373
Storage Temperature:
-20°C
Additional Information:
TARGET: Transcription factor; Antibiotic -- PATHWAY: Transcription; Myc -- RESEARCH AREA: Stem cells -- DISEASE AREA: Infectious disease