FK-506
Supplier:
Catalogue number:
10-1103-02
Size:
50 mg
Product is available in:
FKBP inhibitor / FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50 ~ 1 nM). Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
104987-11-3
Alternative Names:
Tacrolimus
Reference:
1) Yu et al. (2006), Effects of cyclosporine A, FK506 and rapamycin on clacineurin phosphatase activity in mouse brain; IUBMB Life, 58 429
Storage Temperature:
-20°C
Additional Information:
TARGET: PPIase; Phosphatase; Molecular glue -- PATHWAY: Proliferation; Cell cycle; mTOR -- RESEARCH AREA: Immunology -- DISEASE AREA: Infectious disease