Bestatin HCl
Aminopeptidase inhibitor / Inhibits leucine aminopeptidase and aminopeptidases B and N. Inhibits leukotriene A4 hydrolase. Displays immunostimulant activity via activation of macrophages and T lymphocytes. Displays antitumor activity.
Biochemicals & reagents
65391-42-6
1) Orning et al. (1991), Leukotriene A4 hydrolase. Inhibition by bestatin and intrinsic aminopeptidase activity establish its functional resemblance to metallohydrolase enzymes; J. Biol. Chem., 266 1375 2) Wang et al. (2010), The effect of different species aminopeptidase N structure on the activity screening of aminopeptidase N inhibitor; Biol. Pharm. Bull., 33 1658
-20°C
TARGET: Protease; Antibiotic -- PATHWAY: Lipid signaling; Posttranslational modification; Degradation -- RESEARCH AREA: Immunology -- DISEASE AREA: Infectious disease