Mitomycin C
DNA crosslinking and damaging agent / DNA damaging and crosslinking agent. Induces apoptosis in various cell lines. Cell permeable. This product is not approved for human therapeutic use.
Biochemicals & reagents
50-07-7
1) Tee and Proud (2000), DNA-damaging agents cause inactivation of translational regulators linked to mTOR signaling; Oncogene, 30 21 / 2) Park et al. (2000), Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95- independent manner in human gastric adenocarcinoma cells ; Cancer Lett., 158 125 / 3) Merck Index 14:6215
-20°C
TARGET: DNA; Antibiotic -- PATHWAY: DNA damage; Apoptosis inducer; Cell cycle -- RESEARCH AREA: Cell death; Stem cells -- DISEASE AREA: Infectious disease; Cancer