C-178
Supplier:
Catalogue number:
10-4131-01
Size:
10 mg
Product is available in:
STING antagonist / C-178 is an inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.
Product Type:
Biochemicals & reagents
CAS Number:
329198-87-0
Reference:
1) Haag et al. (2018), Targeting STING with covalent small-molecule Inhibitors; Nature 559 269
Storage Temperature:
-20°C
Additional Information:
TARGET: STING -- PATHWAY: Cytokine; Posttranslational modification -- RESEARCH AREA: Immunology; Neuroscience -- DISEASE AREA: Inflammation; Infectious disease