DYRK inhibitor / Enhances stem cell proliferation and protects pluripotency in culture.1 Inhibits Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK).2
Product Type:
Biochemicals & reagents
CAS Number:
147591-46-6
Reference:
1) Miyabayashi et al. (2008), Indole derivatives sustain embryonic stem cell self-renewal in long term culture; Biosci. Biotechnol. Biochem., 72 1242 2) Hasegawa et al. (2012), Wnt signaling orchestration with a small molecule DYRK inhibitor provides long-term xeno-free human pluripotent cell expansion; Stem Cells Translat. Med., 1 18
Storage Temperature:
-20°C
Additional Information:
TARGET: Kinase; Antioxidant -- PATHWAY: Proliferation -- RESEARCH AREA: Stem cells; Oxidative Stress -- DISEASE AREA: Inflammation