Zerumbone
Supplier:
Catalogue number:
10-2247-02
Size:
50 mg
Product is available in:
Enhances apoptosis / Natural sesquiterpene ketone isolated from Zingiber sp. Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Induces apoptosis in T-acute lymphoblastic leukemia cells. Has no cytotoxic effect on normal cells. Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
471-05-6
Reference:
1) Leu et al. (2009), A small molecule inhibitor of inducible heat shock protein 70; Mol. Cell, 36 15 / 2) Abdelwahab et al. (2011), Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells; Leuk. Res., 35 268
Storage Temperature:
-20°C
Additional Information:
TARGET: Cytoskeleton; Antibiotic -- PATHWAY: Apoptosis inducer; Cell cycle -- RESEARCH AREA: Cell death -- DISEASE AREA: Cancer; Infectious disease