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Zerumbone

Supplier:
Catalogue number:
10-2247-02
Size:
50 mg
Product is available in:
  • USA
  • Canada
$190.00 Shipping is calculated in checkout

Enhances apoptosis / Natural sesquiterpene ketone isolated from Zingiber sp. Potentiates TRAIL-induced apoptosis via upregulation of death receptor DR4 and DR5 expression. Induces apoptosis in T-acute lymphoblastic leukemia cells. Has no cytotoxic effect on normal cells. Cell permeable.

Product Type:

Biochemicals & reagents

CAS Number:

471-05-6

Reference:

1) Leu et al. (2009), A small molecule inhibitor of inducible heat shock protein 70; Mol. Cell, 36 15 / 2) Abdelwahab et al. (2011), Zerumbone induces apoptosis in T-acute lymphoblastic leukemia cells; Leuk. Res., 35 268

Storage Temperature:

-20°C

Additional Information:

TARGET: Cytoskeleton; Antibiotic -- PATHWAY: Apoptosis inducer; Cell cycle -- RESEARCH AREA: Cell death -- DISEASE AREA: Cancer; Infectious disease