Camptothecin
Supplier:
Catalogue number:
10-1041-02
Size:
1 g
Product is available in:
Topoisomerase I inhibitor / Camptothecin is a natural product isolated from the chinese Happy tree, Camptotheca acuminate. It is an inhibitor of DNA topoisomerase I. It binds irreversibly to the topoisomerase I /DNA complex preventing DNA re-ligation and generating permanent double strand breaks. Potent antitumor agent.
Product Type:
Biochemicals & reagents
CAS Number:
7689-03-4
Additional Information:
TARGET: Topoisomerase; DNA; Antibiotic -- PATHWAY: DNA synthesis; Transcription; Apoptosis inducer -- RESEARCH AREA: Cell death; Cellular stress -- DISEASE AREA: Cancer; Infectious diseaseObesity