Dehydrozingerone
Glutathione sponge / Dehydrozingerone is a structural half analog of curcumin and is isolated from ginger rhizomes. Dehydrozingerone displays antioxidant, antibacterial and antifungal properties.1 It has also been shown to possess various antitumor effects2,3 and inhibit growth factor/peroxide-stimulated vascular smooth muscle function4.
Biochemicals & reagents
1080-12-2
1) Kubra et al. (2014), Structure-function activity of dehydrozingerone and its derivatives as antioxidant and antimicrobial compounds; J.Food Sci.Technol. 51 245 2) Motohashi et al. (1998), Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation; Cancer Lett. 134 37 3) Yogosawa et al. (2012), Dehydrozingerone, a structural analog of curcumin, induces cell-cycle arrest at the G2/M phase and accumulates intracellular ROS in HT-29 human colon cancer cells; J.Nat.Prod. 75 2088 4) Liu et al. (2008), Inhibitory effect of dehydrozingerone on vascular smooth muscle cell function; J.Cardiovasc.Pharmacol. 52 422
-20°C
TARGET: Glutathione; Antioxidant; Antibiotic -- PATHWAY: Redox -- RESEARCH AREA: Oxidative stress -- DISEASE AREA: Cancer; Infectious disease