Veratramine
Supplier:
Catalogue number:
10-1147-01
Size:
5 mg
Product is available in:
Cyclopamine analog / Veratramine is a teratogenic steroidal alkaloid found in the corn lily (Veratrum sp.)1,2. It is an analog of cyclopamine which can inhibit the hedgehog signaling pathway-dependent proliferation in NIH/3T3 cells at 8 μM1. Cell permeable. SPECIAL HANDLING PRECAUTIONS: This product is teratogenic. Women who are, or may be pregnant should not handle this compound.
Product Type:
Biochemicals & reagents
CAS Number:
60-70-8
Alternative Names:
NSC 17821; NSC 23880
Reference:
1) Tang et al. (2010), Antitumor and antiplatelet activity of alkaloids from veratrum dahuricum; Phytother. Res., 24 821 2) Mahindroo et al. (2009), Hedgehog-Gli signaling pathway inhibitors as anticancer agents; J. Med. Chem., 52 3829
Storage Temperature:
-20°C
Additional Information:
PATHWAY: Hedgehog; Proliferation