Ciglitazone
Supplier:
Catalogue number:
10-1047-02
Size:
25 mg
Product is available in:
PPARγ agonist / PPARgamma agonist (EC50=3 µM). Stimulates adipogenesis in human mesenchymal stem cells. Inhibits HUVEC differentiation and angiogenesis. Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
74772-77-3
Reference:
1) Cantello et al. (1994) [[omega-(Heterocyclylamino)alkoxy]benzyl]-2,4-thiazolidinediones as potent antihyperglycemic agents J. Med. Chem. 37 3977. / 2) Xin et al. (1999) Peroxisome proliferator-activated receptor gamma ligands are potent inhibitors of angiogenesis in vitro and in vivo J. Biol. Chem. 274 9116
Storage Temperature:
-20°C
Additional Information:
TARGET: Transcription factor -- PATHWAY: PPAR; Fatty acid metabolism; Transcription; NFKappaB; Cytokine -- RESEARCH AREA: Stem cells; Angiogenesis; Neuroscience -- DISEASE AREA: Obesity; InflammationDiabetes