MRL-24
Supplier:
Catalogue number:
10-1365-01
Size:
5 mg
Product is available in:
PPARγ partial agonist / Displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. Highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ. Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
393794-17-7
Reference:
1) Choi et al. (2010), Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by CDK5; Nature, 466 451
Storage Temperature:
RT
Additional Information:
TARGET: Transcription factor -- PATHWAY: PPAR; Fatty acid metabolism; Transcription -- DISEASE AREA: Diabetes