DMPO
Spin trap / Hydrophilic spin trap for superoxide, O-, C-, S- and N-centered free radicals. Useful for both in vivo and in vitro studies. Cell Permeable.
Biochemicals & reagents
3317-61-1
1) Nishizawa et al. (2004), Hydroxyl radical generation caused by the reaction of singlet oxygen with the spin trap DMPO, increases significantly in the presence of biological reductants; Mol. Pharmacol., 6 597 2) Shi et al. (2005), Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species; Arch. Biochem. Biophys., 437 59 3) Clement et al. (2005), Assignment of the EPR spectrum of 5,5-dimethyl-1-pyrroline-N-oxide (DMPO) superoxide spin adduct; J. Org. Chem., 70 1198 4) Gomez-Mejiba et al. (2009), Immuno-spin trapping of protein and DNA radicals: “tagging” free radicals to locate and understand the redox process; Free Rad. Biol. Med., 42 530
-20°C
TARGET: Spin trap -- PATHWAY: Redox -- RESEARCH AREA: Oxidative stress