DEPMPO
Spin trap / DEPMPO is a spin trap capable of detecting oxygen, nitrogen, sulfur and carbon-centered free radicials both in vitro and in vivo. Useful for distinguishing between superoxide-dependent pathways of hydroxyl radical generation, and those that are superoxide independent.
Biochemicals & reagents
157230-67-6
1) Liu et al. (1999), Evaluation of DEPMPO as a spin trapping agent in biological systems; Free Radic. Biol. Med., 26 714 2) Shi et al. (2005), Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species; Arch. Biochem. Biophys., 437 59 3) Culcasi et al. (2012), EPR spin trapping evaluation of ROS production in human fibroblasts exposed to cerium oxide nanoparticles: evidence for NADPH oxidase and mitochondrial stimulation; Chem. Biol. Interact., 199 161
-20°C
TARGET: Spin trap -- PATHWAY: Redox -- RESEARCH AREA: Oxidative stress