www.mayflowerbio.com
Sales & Support: 314-485-5210

*

(R)-PFI-2 HCl

Supplier:
Catalogue number:
10-4033-02
Size:
25 mg
Product is available in:
  • USA
  • Canada
$270.00 Shipping is calculated in checkout

Methyltransferase SETD7 inhibitor / Potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pathway signaling in MCF7 cells by altering YAP nuclear localization in a SETD7-dependent manner.

Product Type:

Biochemicals & reagents

CAS Number:

1627607-87-7

Reference:

1) Barsyte-Lovejoy et al. (2014), (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells; Proc. Natl. Acad. Sci. USA 111 12853

Storage Temperature:

-20°C

Additional Information:

TARGET: Protein methyltransferase -- PATHWAY: Chromatin; Posttranslational modification -- RESEARCH AREA: Epigenetics -- DISEASE AREA: Cancer