(R)-PFI-2 HCl
Supplier:
Catalogue number:
10-4033-02
Size:
25 mg
Product is available in:
Methyltransferase SETD7 inhibitor / Potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pathway signaling in MCF7 cells by altering YAP nuclear localization in a SETD7-dependent manner.
Product Type:
Biochemicals & reagents
CAS Number:
1627607-87-7
Reference:
1) Barsyte-Lovejoy et al. (2014), (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells; Proc. Natl. Acad. Sci. USA 111 12853
Storage Temperature:
-20°C
Additional Information:
TARGET: Protein methyltransferase -- PATHWAY: Chromatin; Posttranslational modification -- RESEARCH AREA: Epigenetics -- DISEASE AREA: Cancer