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BML-278

Supplier:
Catalogue number:
10-1063-01
Size:
5 mg
Product is available in:
  • USA
  • Canada
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SIRT1 activator / A structurally novel activator of SIRT1 (EC50=1 µM). Displays selectivity over SIRT2 and 3 (EC50=25 and 50 µM respectively). Cell permeable.

Product Type:

Biochemicals & reagents

CAS Number:

120533-76-8

Reference:

1) Mai et al. (2009), Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors; J. Med. Chem., 52 5496

Storage Temperature:

RT

Additional Information:

TARGET: Protein deacetylase -- PATHWAY: Chromatin; Posttranslational modification -- RESEARCH AREA: Epigenetics; Neuroscience -- DISEASE AREA: Neurodegeneration