BML-278
Supplier:
Catalogue number:
10-1063-01
Size:
5 mg
Product is available in:
SIRT1 activator / A structurally novel activator of SIRT1 (EC50=1 µM). Displays selectivity over SIRT2 and 3 (EC50=25 and 50 µM respectively). Cell permeable.
Product Type:
Biochemicals & reagents
CAS Number:
120533-76-8
Reference:
1) Mai et al. (2009), Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors; J. Med. Chem., 52 5496
Storage Temperature:
RT
Additional Information:
TARGET: Protein deacetylase -- PATHWAY: Chromatin; Posttranslational modification -- RESEARCH AREA: Epigenetics; Neuroscience -- DISEASE AREA: Neurodegeneration