Bithionol
Glutamate dehydrogenase inhibtor / Bithionol is an antihelmintic drug with bacteriostatic and fungicidal properties. Bithionol has also been found to be an inhibitor of glutamate dehydrogenase1,2 (IC50 = 4.8 µM bovine GDH1).
Biochemicals & reagents
97-18-7
1) Li et al. (2009), Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics; J.Biol.Chem. 284 22988 2) Zocher et al. (2012), Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2; Mol.Biochem.Parasitol. 183 52
RT
TARGET: Antibiotic; Dehydrogenase (GAPDH, GPDH, IMPDH, PHGDH, LDH, DHODH, ALDH, GDH, IDH, UGDH, DPD, DHPDH, and MDH) -- PATHWAY: Amino acid metabolism -- DISEASE AREA: Infectious disease