6-Formylindolo(3,2-b)carbazole
Supplier:
Catalogue number:
10-1463-01
Size:
500 ug
Product is available in:
AHR endogenous agonist / Very potent (Kd = 0.07 nM) endogenous ligand for the aryl hydrocarbon receptor (AhR).1,2
Product Type:
Biochemicals & reagents
CAS Number:
172922-91-7
Alternative Names:
FICZ
Reference:
1) Rannung et al (1987) Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances. J.Biol.Chem. 262 15422. 2) Wincent et al. (2009) The Suggested Physiologic Aryl Hydrocarbon Receptor Activator and Cytochrome P4501 Substrate 6-Formylindolo[3,2-b}carbazole is Present in Humans. J.Biol.Chem. 284 2690
Storage Temperature:
-80°C
Additional Information:
TARGET: Transcription factor; Cytochrome/MDR -- PATHWAY: Transcription -- RESEARCH AREA: Stem cells; Immunology; Cancer stem cells; Circadian clock -- DISEASE AREA: Inflammation