Resveratrol
Antioxidant/SIRT1 activator / Naturally occurring phenolic antioxidant. Displays antitumor and antiplatelet effects1. Activates SIRT1 and increases longevity in yeast2. Ameliorates ageing-related phenotypes by inhibition of cAMP phosphodiesterases3.
Biochemicals & reagents
501-36-0
5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
1) Fremont (2000), Biological effects of resveratrol ; Life Sci., 66 663 / 2) Howitz et al. (2003), Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan ; Nature, 425 191 / 3) Park et al. (2012), Resveratrol ameliorates aging-related metabolic phenotypes by inhibiting cAMP phosphodiesterases ; Cell, 148 421
-20°C
TARGET: Protein deacetylase; Antioxidant -- PATHWAY: Chromatin; Redox; Coagulation; Cell cycle; Apoptosis inducer; Apoptosis inhibitor -- RESEARCH AREA: Epigenetics; Cell death; Immunology; Stem cells -- DISEASE AREA: Cancer; DiabetesAgeing; Inflammation; Neurodegeneration