MCSF, mouse recombinant
Macrophage colony stimulating factor (MCSF) is one of the glycoproteins called colony-stimulating factors (CSFs). A mononuclear phagocyte colony-stimulating factor (MCSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. Some clinical investigations have shown autologous production of MCSF various human cell lines in vitro and by tumors in vivo. Recombinant Mouse MCSF is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing two 156 amino acid chains and with a total molecular weight of 36.8 kDa.
Peptides & proteins
MGI-IM, CSF-1
at -20°C
at least 12 months
NAME: Macrophage Colony Stimulating Factor; ACCESSION/UNIPROT#: P07141; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: NFS-60 cell proliferation with an acceptance criteria of 10 ng/mL (ED50), 1 x 10^5 units/mg.; #AA: 312; SEQUENCE: MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP