IL-4, human recombinant
Interleukin-4 (IL-4), produced primarily by CD4(+) T cells, is an immunomodulatory cytokine, which can inhibit the growth of tumour cells. IL-4 has been known as a Th2 cytokine and can act on B cells, T cells, and monocytes. IL-4 exhibits antitumor activity in rodent experimental gliomas, which is likely mediated by the actions of IL-4 on a variety of immune cells present in and around the tumor masses. Recombinant Human IL-4 produced in E. coli is a single, non-glycosylated polypeptide chain.
Peptides & proteins
B cell Stimulating Factor, BSF-1, BCDF, BCGF
at -20°C
at least 12 months
NAME: Interleukin-4; ACCESSION/UNIPROT#: P05112; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: TF-1 cell proliferation with an acceptance criteria of 250 pg/mL (ED50), 4 x 10^6 units/mg.; #AA: 130; SEQUENCE: MHKCDITLQE IIKTLNSLTE QKTLCTELTV TDIFAASKNT TEKETFCRAA TVLRQFYSHH EKDTRCLGAT AQQFHRHKQL IRFLKRLDRN LWGLAGLNSC PVKEANQSTL ENFLERLKTI MREKYSKCSS