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Myostatin, human recombinant

Catalogue number:
GFH22-1000
Size:
1 mg
Product is available in:
  • USA
  • Canada
$6007.00 Shipping is calculated in checkout

Myostatin (GDF8) is a member of the transforming growth factor beta superfamily that is essential for proper regulation of skeletal muscle mass. Myostatin is a secreted protein that negatively regulates skeletal muscle mass determining both muscle fiber number and size. The myostatin pathway is conserved and regulates muscle mass in a number of animal species ranging from fish to humans. Inhibition of myostatin using a variety of therapeutic approaches can increase muscle mass in a number of animal models of human disease, including muscular dystrophy. Recombinant Human Myostatin is a homodimer, non-glycosylated polypeptide chain.

Product Type:

Peptides & proteins

Alternative Names:

GDF-8, MSTN

Storage Temperature:

-20°C

Additional Information:

NAME: Myostatin; ACCESSION/UNIPROT#: O14793(267-375); EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile 20 mM HCI at 0.1 mg/mL.; TESTING: MCP-11 cell cytoxicity with an acceptance criteria of 50 ng/mL (ED50), 2.0 x 10^4 units/mg.; #AA: 218; SEQUENCE: DFGLDCDEHS TESRCCRYPL TVDFEAFGWD WIIAPKRYKA NYCSGECEFV FLQKYPHTHL VHQANPRGSA GPCCTPTKMS PINMLYFNGK EQIIYGKIPA MVVDRCGCS