Staurosporine
StemRegenin 1 is an AhR inhibitor. StemRegenin 1 induces CD34+ cell expansion by binding and antagonizing AhR. StemRegenin 1 treatment accelerates the proliferation of CD34+ cells. Sequential co-culture with BMP-4, PGE2, and StemRegenin 1 leads to robust Macaca nemestrina iPSC hematopoietic progenitor cell formation. Culture of mPB CD34+ cells with cytokines plus StemRegenin 1 increases the number of CD34+, CD133+ and CD90+ hematopoietic stem and progenitor cell populations compared to control cells. StemRegenin 1 promotes human plasmacytoid and myeloid dendritic cell development from CD34+ hematopoietic progenitor cells.
Peptides & proteins
1227633-49-9
SR1, 4-[2-[[2-benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]-phenol