Fumonisin B1
Supplier:
Catalogue number:
10-2396-02
Size:
5 mg
Product is available in:
Blocks sphingolipid biosynthesis / Inhibits ceramide synthesis (sphinganine N-acyltransferase), IC50 = 100 nM. Inhibits de novo sphingolipid biosynthesis (IC50 = 0.7 µM) thereby blocking glycosphingolipid production.
Product Type:
Biochemicals & reagents
CAS Number:
116355-83-0
Reference:
1) Merrill et al. (1993), Fumonisin B1 inhibits sphingosine (sphinganine) N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ ; J. Biol. Chem., 268 27299
Storage Temperature:
-20°C
Additional Information:
PATHWAY: Sphingolipid metabolism; Apoptosis inhibitor -- RESEARCH AREA: Cell death