Ursolic acid
Angiogenesis inhibitor / Inhibits endothelial cell proliferation and migration (IC50=5 µM) and angiogenesis.1 Promotes skeletal muscle rejuvenation via enhanced SIRT1 expression.2 Induces apoptosis in malignant mesothelioma cells.3
Biochemicals & reagents
77-52-1
1) Sohn et al. (1995), Anti-angiogenic activity of triterpene acids; Cancer Lett., 94 213 2) Bakhtiari et al. (2016), Short-term ursolic acid promotes skeletal muscle rejuvenation through enhancing of SIRT1 expression and satellite cells proliferation; Biomed. Pharmacother., 78 185 3) Sohn et al. (2016), Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell; J. Biol. Sci., 12 1279
-20°C
PATHWAY: Apoptosis inducer; Proliferation; Cell migration -- RESEARCH AREA: Epigenetics; Cell death; Angiogenesis -- DISEASE AREA: Cancer; InflammationDiabetes