7-Dehydrocholesterol
Supplier:
Catalogue number:
10-3941-02
Size:
1 g
Product is available in:
Endogenous cholesterol precursor / Ferroptosis inhibitor / 7-Dehydrocholesterol is an endogenous cholesterol precursor and is photochemically converted to vitamin D3 in the skin.1 It has recently been found to be an endogenous suppressor of ferroptosis and can confer a prosurvival state in cancer cells.2
Product Type:
Biochemicals & reagents
CAS Number:
434-16-2
Alternative Names:
Provitamin D3
Reference:
1) MacLaughlin et al. (1982), Spectral character of sunlight modulates photosynthesis pf previtamin D3 and its photoisomers in human skin; Science, 216 1001 2) Freitas et al. (2024), 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis; Nature, 626 401
Storage Temperature:
-20°C
Additional Information:
PATHWAY: Ferroptosis; Cholesterol metabolism -- RESEARCH AREA: Cell death -- DISEASE AREA: Cancer