ML324
Supplier:
Catalogue number:
10-1455-02
Size:
25 mg
Product is available in:
JMJD2 inhibitor / Inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. Represses the reactivation of HSV from the latent state in sensory neurons1.
Product Type:
Biochemicals & reagents
CAS Number:
1222800-79-4
Reference:
1) Liang et al. (2013), Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med., 5 167ra5
Storage Temperature:
-20°C
Additional Information:
TARGET: Protein demethylase -- PATHWAY: Chromatin; Posttranslational modification -- RESEARCH AREA: Epigenetics -- DISEASE AREA: Infectious disease