Lactacystin
Supplier:
Catalogue number:
10-1314-02
Size:
1 mg
Product is available in:
Proteasome inhibitor / Specific inhibitor of three proteolytic activities of the proteasome. Chymotrypsin-like activity is inhibited most potently followed by trypsin-like activity. Inhibition of the peptidyl-glutamyl peptide hydrolytic activity is relatively weak.
Product Type:
Biochemicals & reagents
CAS Number:
133343-34-7
Reference:
1) Omura et al. (1991), Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells ; J. Antibiot., 44 113 / 2) Fenteany et al. (1995), Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin ; Science, 268 726
Storage Temperature:
-20°C
Additional Information:
TARGET: Proteasome -- PATHWAY: Degradation; Cell cycle -- RESEARCH AREA: Ubiquitin/Proteasome