GRL-0667
Supplier:
Catalogue number:
10-4963-01
Size:
5 mg
Product is available in:
Noncovalent inhibitor of SARS-CoV PLpro / Potent (IC50 = 320 nM) noncovalent inhibitor of severe acute respiratory syndrome-coronavirus papain-like protease (SARS-CoV PLpro). GRL-0667 inhibited SARS-CoV viral replication in Vero E6 cells with no cytotoxicity (EC50 = 9.1 µM).1
Product Type:
Biochemicals & reagents
CAS Number:
1234195-91-5
Reference:
Ghosh et al. (2010), Severe Acute Respiratory Syndrome-Coronavirus Papain-Like Novel Protease Inhibitors: Design, Synthesis, Protein-Ligand X-ray Structure and Biological Evaluation; J. Med. Chem. 53 4968
Storage Temperature:
-20°C
Additional Information:
TARGET: Protease -- DISEASE AREA: Infectious disease