Apixaban
Factor Xa inhibitor / Potent and selective inhibitor of both free and prothrombin-bound factor Xa, Ki = 0.8 nM.1 Clinically useful antithrombotic agent.2 Apixaban lowered risk of recurrent venous thromboembolism and major bleeding in high-risk patients.3
Biochemicals & reagents
503612-47-3
BMS-562247-01
1 Turpie et al. (2007), Oral, direct factor Xa inhibitors in development for the prevention and treatment of thromboembolic diseases; Arterioscler. Vasc. Biol., 27 1238 2 Lai et al. (2022), Effects of oral anticoagulant therapy in patients with pulmonary diseases; Front. Cardiovasc. Med., 9 987652 3 Cohen et al. (2022), Effectiveness and safety of apixaban vs warfarin among venous thromboembolism patients at high-risk of bleeding; PLoS One, 17 e0274969
-20°C
TARGET: Protease -- PATHWAY: Coagulation -- DISEASE AREA: Heart disease