RO 20-1724
Supplier:
Catalogue number:
10-1014-01
Size:
50 mg
Product is available in:
PDE4 inhibitor / Selective inhibitor of cAMP-specific phosphodiesterase (PDE4), IC50 = 0.2 µM. Displays anti-inflammatory activity. Cell permeable
Product Type:
Biochemicals & reagents
CAS Number:
29925-17-5
Reference:
1) Soderling et al. (1998), Cloning and characterization of a cAMP-specific cyclic nucleotide phosphodiesterase; Proc. Natl. Acad. Sci. USA, 95 8991 / 2) Nicholson et al. (1991), Differential modulation of tissue function and therapeutic potential of selective inhibitors of cyclic nucleotide phosphodiesterase isoenzymes; Trends Pharmacol. Sci., 12 19
Storage Temperature:
RT
Additional Information:
TARGET: PDE (Phosphodiesterase) -- PATHWAY: cAMP / cGMP signaling -- RESEARCH AREA: Immunology -- DISEASE AREA: Inflammation