U-74389G
Free radical scavenger / U-74389G is an antioxidant and Inhibits iron-mediated lipid peroxidation.1 It has also been shown to reduce free radical-mediated injury after ischemia and reperfusion.2,3
Biochemicals & reagents
153190-29-5
1) Braughler et al (1987) Novel 21-aminosteroids as potent inhibitors of iron-dependent lipid peroxidation. J.Biol.Chem. 262 10438 / 2) Campo et al. (1996) Protection of ischemic and reperfused rat myocardium by the nonglucocorticoid 21-aminosteroid U-74389G, a new inhibitor of lipid peroxidation J. Pharmacol. Exp. Ther. 277 333 / 3) Perna et al. (1996) Protection of rat heart from ischaemia-reperfusion injury by the 21-aminosteroid U-74389G Pharmacol. Res. 34 25
-20°C
TARGET: Antioxidant -- PATHWAY: Redox; Fatty acid metabolism; Apoptosis inhibitor -- RESEARCH AREA: Cell death -- DISEASE AREA: Ischemia