NADH oxidase inhibitor / Naturally occurring antagonist of dihydrostreptomycin. Potent inhibitor of the respiratory chain binding to the mitochondrial cytochrome b protein. Inhibits NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR).
Product Type:
Biochemicals & reagents
CAS Number:
341-88-8
Reference:
1) Nakayama et al. (1999), Inhibitor studies of a new antibiotic, korormicin, 2-n-heptyl-4-hydroxyquinoline N-oxide and Ag+ toward the Na+-translocating NADH-quinone reductase from the marine Vibrio alginolyticus; Biol. Pharm. Bull., 22 1064
Storage Temperature:
-20°C
Additional Information:
TARGET: Nox (NADH/NADPH oxidase); Cytochrome/MDR; Energy production -- PATHWAY: Redox; NAD, NADP pathways -- DISEASE AREA: Infectious disease