PODS® Human IL-3

PODS® Human IL-3 contains the polyhedrin protein co-crystallized with Human IL-3. IL-3 stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells and various lineage-committed progenitors. In addition, IL-3 plays important roles in neuronal cell proliferation, stimulation of mature basophils and the activation of monocytes. Its secretion is predominantly mediated by T lymphocytes and mast cells, signal transduction is mediated by the IL-3 receptor. Human IL-3 does not show bioactivity on murine cells due to significant amino acid divergence between human and murine IL-3.