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Bromosporine

Supplier:
Catalogue number:
10-4030-02
Size:
25 mg
Product is available in:
  • USA
  • Canada
$275.00 Shipping is calculated in checkout

Pan-bromodomain inhibitor / Bromosporine is a potent pan-Bromodomain (BRD) inhibitor.1 Bromosporine was able to reactivate HIV-1 replication in different latency models.2

Product Type:

Biochemicals & reagents

CAS Number:

1619994-69-2

Reference:

1) Picaud et al. (2016), Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia; Sci.Adv. 2 e1600760 2) Pan et al. (2017), The bromodomain and extraterminal domain inhibitor bromosporine synergistically reactivates latent HIV-1 in latently infected cells; Oncotarget 8 94104

Storage Temperature:

-20°C

Additional Information:

TARGET: Bromodomain -- PATHWAY: Chromatin; Posttranslational modification -- RESEARCH AREA: Epigenetics; Neuroscience -- DISEASE AREA: Cancer; InflammationInfectious disease