Oseltamivir phosphate
Neuroamidase inhibitor / Antiviral / Oseltamivir phosphate (204255-11-9) is a potent viral neuraminidase inhibitor and a clinically useful treatment for influenzas A and B.1,2 Oseltamivir is a prodrug that is converted to the active acid in vivo – IC50 for active acid in vitro = 2 nM.3
Biochemicals & reagents
204255-11-8
GS4104; Tamiflu
1) Sidwell et al. (1998), Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor; Antiviral Res., 37 107 2) McClellan and Perry (2001), Oseltamivir: A Review of Its Use in Influenza; Drugs, 61 263 3) Li et al. (1998), Identification of GS4104 as an orally bioavailable prodrug of the influenza virus neuraminidase inhibitor GS4071; Antimicrob. Agents Chemother., 42 647
-20°C
TARGET: Glycosylation -- DISEASE AREA: Infectious disease