TPO, human recombinant
Thrombopoietin (TPO) is a growth factor that is produced by the liver and kidney. TPO acts through the TPO receptor to promote megakaryocyte maturation and differentiation, which leads to the production of platelets. Recombinant human TPO is a non-glycosylated protein, containing the 174 amino acids of the receptor binding domain and having a molecular mass of 18.6 kDa.
Peptides & proteins
Megakaryocyte Colony Stimulating Factor, c-MPL ligand, MGDF
at -20°C
at least 12 months
NAME: Thrombopoietin; ACCESSION/UNIPROT#: P40225; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: MO7e cell proliferaiton with an acceptance criteria of 5 ng/mL (ED50), 2 x 10^5 units/mg.; #AA: 175; SEQUENCE: MSPAPPACDL RVLSKLLRDS HVLHSRLSQC PEVHPLPTPV LLPAVDFSLG EWKTQMEETK AQDILGAVTL LLEGVMAARG QLGPTCLSSL LGQLSGQVRL LLGALQSLLG TQLPPQGRTT AHKDPNAIFL SFQHLLRGKV RFLMLVGGST LCVRRAPPTT AVPSRTSLVL TLNEL