PlGF-3, human recombinant
Placenta Growth Factor (PlGF) is a member of the Vascular Endothelial Growth Factor (VEGF) / Platelet-Derived Growth Factor (PDGF) family of growth factors that share a conserved pattern of eight cysteines. PlGF is detected in the placenta, heart, lungs, thyroid, and adipose tissues. These growth factors induce monocyte activation, migration, and production of inflammatory cytokines and VEGF. There are four alternatively spliced PlGF isoforms (PlGF-1, PlGF-2, PlGF-3, and PlGF-4), each with unique secretion patterns and heparin-binding affinities. PlGF-3 is an angiogenic factor, which promotes endothelial cell growth and angiogenesis, being expressed exclusively in the placenta.
Peptides & proteins
Placenta Growth Factor-3, PGFL, Placenta Growth Factor, D12S1900, PGF, PGFL, placenta growth factor, placental growth factor, placental growth factor, vascular endothelial growth factor-related protein, PlGF, PlGF-2, PLGFplacental growth factor-like, SHGC
NAME: PlGF-3; ACCESSION/UNIPROT#: P49763; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; #AA: 204 / 408; SEQUENCE: MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRHSPGRQ SPDMPGDFRA DAPSFLPPRR SLPMLFRMEW GCALTGSQSA VWPSSPVPEE IPRMHPGRNG KKQQRKPLRE KMKPERCGDA VPRR