PODS® Human TGF-β 2

PODS® Human TGF-β 2 contains the polyhedrin protein co-crystalized with Human TGF-β2. Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-β family of proteins signal through serine/threonine kinase receptors. TGF-β isoforms (TGF-β1, -β 2, and -β 3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-β2 demonstrates cross-species reactivity. TGF-β2may have an autocrine function in enhancing tumour growth by supressing immunosurveillance of tumour development.