Activin A, rat recombinant
Activin A is a member of the TGF-beta family of proteins produced by many cell types throughout development. Activins interact with Type I and Type II serine/threonine kinases to signal to SMAD proteins to regulate a variety of functions, including cell proliferation, differentiation, wound healing, apoptosis and metabolism. Activin A is a homodimer of two beta A chains and is not biologically active until the N terminal propeptide is cleaved from each. Rat Activin A has 100% amino acid sequence identity to human, mouse, porcine, bovine and feline proteins. Recombinant rat Activin A is a non-glycosylated homodimer.
Peptides & proteins
Inhibin beta-1, FRP, FSH-releasing protein
at -20°C
at least 12 months
NAME: Activin A; ACCESSION/UNIPROT#: P18331; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: Cytotoxicity of MPC-11 cells with an acceptance criteria of 10 ng/mL (ED50), 1 x 10^5 units/mg.; #AA: 234; SEQUENCE: MGLECDGKVN ICCKKQFFVS FKDIGWNDWI IAPSGYHANY CEGECPSHIA GTSGSSLSFH STVINHYRMR GHSPFANLKS CCVPTKLRPM SMLYYDDGQN IIKKDIQNMI VEECGCS