VEGF-165, mouse recombinant
Vascular endothelial growth factor-A (VEGF-A) was originally isolated from tumor cells and referred to as Tumor Angiogenesis Factor or Vascular Permeability Factor. Although expressed at high levels in certain tumor-derived cells, it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several variants, VEGF-165 being the most abundant. Recombinant mouse VEGF-165 is a non-glycosylated homodimer.
Peptides & proteins
VEGF-A, VPF, glioma-derived endothelial cell mitogen
-20°C
NAME: Vascular Endothelial Growth Factor-165; ACCESSION/UNIPROT#: Q00731-2; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: HUVEC proliferation with an acceptance criteria of 10 ng/mL (ED50), 1.0 x 10^5 units/mg.; SEQUENCE: MAPTTEGEQK SHEVIKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNITMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPENHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR