IL-13, mouse recombinant
Interleukin-13 (IL-13) is an important cytokine secreted from Th2 cells. The functions attributed to IL-13 overlap significantly with those of IL-4 (induces IgE secretion from B cells and inhibits expression of inflammatory cytokines such as IL-1 beta, TNF-alpha, IL-8 and IL-6), but differs from IL-4 in that IL-13 seems to link inflammatory response of immune cells to the pathophysiological changes in the surrounding non-immune cells. The receptor subunits of IL-13 consist of IL-4Rα, IL-13Rα1 and IL-13Rα2. Human and mouse IL-13 are cross-reactive. Recombinant mouse IL-13 is a non-glycosylated protein.
Peptides & proteins
NC30
-20°C
NAME: Interleukin-13; ACCESSION/UNIPROT#: P20109; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile 20 mM HCI at 0.1 mg/mL.; TESTING: TF-1 cell proliferation with an acceptance criteria of 10 ng/mL (ED50), 1 x 10^5 units/mg.; #AA: 111; SEQUENCE: MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F