IL-5, mouse recombinant
Mouse Interleukin-5 (IL-5) is a glycoprotein also known as EDF and TRF. It is involved in B-cell growth and eosinophil activation. IL-5 has been shown to be expressed in Th2, mast cells and eosinophils and is regulated by GATA-3, in addition to other transcription factors. IL-5 signals its biological effect through interaction with the IL-5 receptor (IL-5R). Recombinant mIL-5 is comprised of two chains forming a disulfide-linked homodimer.
Peptides & proteins
EDF, BCDFII, TRF
-20°C
NAME: Interleukin-5; ACCESSION/UNIPROT#: P04401; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 20 mM sodium bicarbonate, pH 9.0. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: TF-1 cell proliferation with an acceptance criteria of 2 ng/mL (ED50), 5 x 10^5 units/mg.; #AA: 226; SEQUENCE: MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG