IFN-α 2b, human recombinant
Interferon-alpha 2b (IFN-alpha 2b) is a Type I interferon made by leukocytes during viral infection. It has anti-viral and non-proliferative activity induced by JAK1-STAT signaling. IFN-alphas are the most widely used type for therapeutic purposes. IFN-alpha 2b is a variant of IFN-alpha 2a that differs by one amino acid. Recombinant human IFN-alpha 2b is a non-glycosylated protein.
Peptides & proteins
Type I Interferon, Alpha 2
-20°C
NAME: Interferon-alpha 2b; ACCESSION/UNIPROT#: P01563 (VAR_004012); EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: Viral CPE assay using EMC virus on A549 cells with an acceptance criteria of 2.0 x 10^8 units/mg.; #AA: 166; SEQUENCE: MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE