NGF-β, human recombinant
Nerve Growth Factor (NGF-beta) is a neurotrophic factor related to BDNF, NT-3 and NT-4. NGF-beta acts through its receptor beta-NGFR, and is involved in the development and maintenance of the sensory and sympathetic nervous systems. NGF-beta is also involved in the growth, differentiation and survival of B lymphocytes. Human, mouse and rat proteins show cross-reactivity. Recombinant human NGF-beta is a non-covalently linked homodimer.
Peptides & proteins
β-NGF
-20°C
NAME: Nerve Growth Factor beta; ACCESSION/UNIPROT#: P01138; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: TF-1 cell proliferation with an acceptance criteria of 5 ng/mL (ED50), 2 x 10^5 units/mg.; #AA: 242; SEQUENCE: MSSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVRRA