MCSF, human recombinant
Macrophage colony stimulating factor (MCSF) is one of the glycoproteins called colony-stimulating factors (CSFs). A mononuclear phagocyte colony-stimulating factor (MCSF) synthesized by mesenchymal cells. The compound stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. Some clinical investigations have shown autologous production of MCSF various human cell lines in vitro and by tumors in vivo. Recombinant Human MCSF is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing two 159 amino acid chains and with a total molecular weight of 36.8 kDa.
Peptides & proteins
MGI-IM, CSF-1
at -20°C
at least 12 months
NAME: Macrophage Colony Stimulating Factor; ACCESSION/UNIPROT#: P09603; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 8.0. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: TF-1 cell proliferation with an acceptance criteria of 200 pg/mL (ED50), 5.0 x 10^6 units/mg.; SEQUENCE: MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS