PDGF-BB, human recombinant
Platelet Derived Growth Factor - BB (PDGF-BB) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF. PDGF-BB Human Recombinant is a homodimeric, non-glycosylated, polypeptide chain.
Peptides & proteins
GDGF, ODGF
at -20°C
at least 12 months
NAME: Platelet Derived Growth Factor-BB; ACCESSION/UNIPROT#: P01127; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5. Reconstitute in sterile water at 0.1 mg/mL.; TESTING: NR6R-3T3 Proliferation with an acceptance criteria of 20 ng/mL (ED50), 5.0 x 10^4 units/mg.; #AA: 220; SEQUENCE: MSLGSLTIAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRNVQ CRPTQVQLRP VQVRKIEIVR KKPIFKKATV TLEDHLACKC ETVAAARPVT