PDGF-AA, human recombinant
Platelet Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets. It is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-alpha, TGF-beta and EGF. Recombinant Human PDGF-AA is a homodimeric, non-glycosylated, polypeptide chain.
Peptides & proteins
GDGF, ODGF
-20°C
NAME: Platelet Derived Growth Factor-AA; ACCESSION/UNIPROT#: P04085; EXPRESSION SYSTEM: E.coli; FORMAT: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA). Reconstitute in sterile water at 0.1 mg/mL.; TESTING: NR6R-3T3 Proliferation with an acceptance criteria of 50 ng/mL (ED50), 2.0 x 10^4 units/mg.; #AA: 252; SEQUENCE: MSIEEAVPAVC KTRTVIYEIP RSQVDPTSAN FLIWPPCVEV KRCTGCCNTS SVKCQPSRVH HRSVKVAKVE YVRKKPKLKE VQVRLEEHLE CACATTSLNP DYREEDTGRP RESGKKRKRK RLKPT